Prototype drug
Multi-drug resistant tuberculosis (MDR-TB) is associated with high treatment failure due to low adherence of patients in` undergoing the complex treatment process. We will follow up with usability testing before implementing the app in a real setting. The app has been tested using four scenarios. Conclusion: TOMO app has contributed to the limited body of literature on improving TB-MDR adherence with digital health intervention, especially using a health app. We have successfully tested the functionalities based on four use cases: patients with high adherence, patients with low adherence, patients with adverse events, and patients following treatment in the primary health center without any visit to the MDR-TB center. The app prototype features include adverse event records and reports, medication-taking reminders, and communication between the patient and the TB-MDR case manager. Results: TOMO app could be used by patients, primary health centers, clinical teams, and case managers. MDR-TB treatment guideline from the Indonesian Ministry of Health was used to develop functionalities of the app for improving adherence. We adopted the Principles for Digital Development to develop and design the app. Methods: It is a design thinking process involving two MDR-TB referral centers, district health offices, primary health centers, and MDR-TB patients in Central Java and Yogyakarta, Indonesia. Objective: This paper aims to present the sequential steps to develop the app, its general architecture, and its functionalities.
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Driven by the increasing use and penetration of a smartphone and the End of TB Strategy that seeks for digital health solution, Center for Tropical Medicine Universitas Gadjah Mada has developed TOMO, an Android-based app for improving medication adherence in MDR-TB. Background: Drug resistance and multi drugs tuberculosis (DR/MDR-TB) are associated with patients' low adherence to undergoing complex treatment.